Pharmacotherapy Challenges of Fontan-Associated Plastic Bronchitis: A Rare Pediatric Disease
نویسندگان
چکیده
منابع مشابه
Pharmacotherapy challenges of Fontan-associated plastic bronchitis: a rare pediatric disease.
Pediatric pharmacotherapy is often challenging due to the paucity of available clinical data on the safety and efficacy of drugs that are commonly used in children. This quandary is even more prevalent in children with rare diseases. Although extrapolations for dosing and administration are often made from available adult data with similar disease states, this translation becomes even more prob...
متن کاملA Rare Case of Idiopathic Plastic Bronchitis
Plastic bronchitis is a rare disorder characterized by formation of large, branching bronchial casts, which are often expectorated. We present an interesting case of a 35-year-old woman who presented for evaluation of a chronic cough productive of voluminous secretions. Clinical and radiological examination confirmed a total left lung atelectasis without any pathological mediastinal node. Flexi...
متن کاملRisk Factors and Outcome of Fontan‐Associated Plastic Bronchitis: A Case‐Control Study
BACKGROUND The onset of plastic bronchitis (PB) can be debilitating in survivors of Fontan surgery. The rarity of this complication makes designing studies to understand risk factors for PB challenging. This 2-center case-control study aimed to describe patient outcomes and to assess the association of antecedent patient factors with PB development. METHODS AND RESULTS Using center registries...
متن کاملSuccessful treatment of plastic bronchitis by selective lymphatic embolization in a Fontan patient.
Plastic bronchitis is a rare and often fatal complication of single-ventricle surgical palliation after total cavopulmonary connection. Although lymphatic abnormalities have been postulated to play a role in the disease process, the etiology and pathophysiology of this complication remain incompletely understood. Here we report on the etiology of plastic bronchitis in a child with total cavopul...
متن کامل[Plastic bronchitis].
Bronchitis plastica is a rare disorder that can occur at any age. It is characterised by formation of large, branching bronchial casts, which are often expectorated, but may be discovered only by bronchoscopy. In most cases, bronchial casts are secondary to underlying diseases of the lung, heart or lymph vessels. We report a case of plastic bronchitis associated with bilateral chylothorax. Prog...
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ژورنال
عنوان ژورنال: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy
سال: 2013
ISSN: 0277-0008
DOI: 10.1002/phar.1290